Night-Time Relax Formula

A daily food supplement to help you find a better sleep. Made with botanicals Lemon Balm, Lavender & Hops. This formula also provides vitamins and minerals to maintain psychological and nervous function, regulate hormone activity and blood glucose levels, in addition to mental performance and stress management which will help you relax and unwind in order to get a great night’s sleep.

The Manuka honey is sourced from our very own Manuka Doctor hives nestled in the luscious green mountains of New Zealand. The honey is freeze dried into powder form and added to our formula which is lovingly made in the UK to the very highest standard. The MGO (methylglyoxal) level in Manuka Honey is derived from DHA (dihydroxyacetone) which is naturally present in the nectar of the Manuka Bush.

Plant-derived capsule shell

Lemon Balm (Melissa officinalis) is a frequently used sleeping remedy for the elderly (lutoMSki, 2000). A 15-day pilot study showed that in a stressed group, Lemon balm leaf extract reduced anxiety and insomnia related to anxiety. In another study it was found that Lemon balm extract significantly reduced the time of falling asleep and extended sleep time. It was also shown that the mixture with lavender extract (Lavandula angustifolia) had a synergistic effect in terms of length of falling asleep and the sleep itself, which may be important in the treatment of insomnia (hajhaSheMi and Safaei, 2015). [1]

A separate study into the extract of stems and flowers of Lavender produced significant sedative effect compared to diazepam. [2]

There is strong evidence that Hops (Humulus lupuls L.) have been used safely for over 30 years to relieve mental stress and to aid sleep and so have been approved by the Committee on Herbal Medicinal Products (HMPC) on their ‘traditional use’. [3]

Vitamin B6 plays an important role in the synthesis of amino acid GABA, tryptophan, and serotonin all of which impact sleep. [4] GABA is produced naturally in the brain. When levels of GABA increase, it suppresses the central nervous system to reduce excitability and, when bound, produces a calming effect that may support a reduction in stress anxiety, and sleeplessness. [5,6] Tryptophan is an amino acid that plays a role in the production of serotonin, the “happy hormone” that helps stabilize our mood. For this reason, vitamin B6 deficiencies have been linked to irritability, emotional disturbances, and disrupted sleep. [7,8]

There is some evidence to support B12 as a regulator of the sleep-wake cycle due to its role in modulating production of melatonin, the sleep hormone, and keeping the circadian rhythms in sync. [9] The vitamin helps increase the production of melatonin during the night-time hours, as well as release it earlier, making it easier to fall and stay asleep. A study published in Neuropsychopharmacology looked at the effects of methyl- and cyanocobalamin on circadian rhythms, well-being, alertness, and concentration in healthy volunteers [10]. They found that methyl B12 (methylcobalamin) was more effective for improving daytime alertness and concentration and shortened and improved sleep patterns in healthy volunteers.

Sources
[1] Katarzyna Swiader et al. The therapeutic properties of Lemon balm (Melissa officinalis): Reviewing novel findings and medical indications. Journal of Applied Botany and Food Quality. Vol 92:327-335. November 2019.
[2] Alnamer, R.; Alaoui, K.; Bouidida, E.H.; Benjouad, A.; Cherrah, Y. Sedative and hypnotic activities of the methanolic and aqueous extracts of Lavandula officinalis from Morocco. Adv. Pharmacol. Sci. 2011, 2012.
[3] EMA. Hop Strobile, Humulus lupulus L. Flos; EMA/HMPC/304459/2016; EMA: Amsterdam, The Netherlands, 2016
[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772032/
[5] https://www.tandfonline.com/doi/abs/10.1080/09637480802558508
[6] https://link.springer.com/article/10.1007/s00726-011-1206-6
[7] https://pubmed.ncbi.nlm.nih.gov/9625217/
[8]https://journals.sagepub.com/doi/abs/10.1177/0031512518770326?journalCode=pmsb&
[9] Okawa M, Mishima K, Nanami T, et al. Vitamin B12 treatment for sleep-wake rhythm disorders. Sleep. 1990;13(1):15-23.
[10] Mayer G, Kröger M, Meier-Ewert K. Effects of vitamin B12 on performance and circadian rhythm in normal subjects. Neuropsychopharmacology. 1996;15(5):456-464.

Take one capsule, one hour before bed. Do not exceed this recommended daily dose. This product should not be used as a substitute for a varied, balanced diet and healthy lifestyle. Please keep out of reach from children.

Discontinue use and consult a doctor if adverse reactions occur. Avoid this product if you have allergies to pollen, bees or bee products. Do not use this product without first consulting with your doctor if you are under medical supervision, on prescribed medication, pregnant, breastfeeding, have asthma or related allergies.

Please note that a signature is required on all of our delivery options.

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Our European service delivers to the following countries: Austria, Belgium, Czech Republic, Denmark, France, Germany, Italy, Luxembourg, Netherlands, Republic of Ireland, Slovakia, Spain.

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Our European Plus service delivers to the following countries: Bulgaria, Croatia, Estonia, Finland, Greece, Hungary, Latvia, Lithuania, Poland, Portugal, Romania, Slovenia, Sweden.

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If you order Products from our site for delivery to one of the International Delivery Destinations, your order may be subject to import duties and taxes which are applied when the delivery reaches that destination. Please note that we have no control over these charges and we cannot predict their amount. You will be responsible for payment of any such import duties and taxes. Please contact your local customs office for further information before placing your order.

You must comply with all applicable laws and regulations of the country for which the Products are destined. We will not be liable or responsible if you break any such law.

Returns

1. You have the right to cancel your purchase in accordance with condition 8 of our terms and conditions. The easiest way to do so is to use our cancellation process by clinking on the following link.

2. If you do cancel your purchase after the products have been despatched by us to you or, after you have received the products, you must return them to us unopened and unused. We will only be obliged to process your refund after we receive the products back from you.

3. We will refund to you the price of the products but we will be permitted to reduce your refund to reflect any reduction in the value of the products which is caused by you handling the products in a way which would not be permitted in a shop.

4. We will refund you for your delivery costs provided that any such refund will be limited to the least expensive delivery option we offer.

5. If you have returned the products to us because they are faulty or mis-described, we will refund the price of a defective product in full, any applicable delivery charges, and any reasonable costs you incur in returning the item to us.